Categories:
Nonclinical, Technology and General Science
Microphysiological Systems / Complex Cell Cultures / 3Rs
Management / Business Development
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Nonclinical Sciences & Technology
May 19-20
Pushing Boundaries in Emerging Infectious Disease Research
In this symposium, scientists will highlight innovative approaches for studying pathogens, monitoring infections, and mitigating infectious threats.
May 19
Beyond Exposure: Integrating PK/PD for Translational Predictive Power Mechanistic Modeling: Moving beyond descriptive data to build predictive exposure–response models.
- Strategic Biomarker Integration: Selecting and validating the right markers to confirm target engagement.
- Dose Optimization: Pinpointing the therapeutic window for NCEs, large molecules, and ADCs.
- Cross-Modality Insights: Navigating the unique PK/PD challenges of diverse therapeutic platforms.
- Risk Mitigation: Solidifying First-in-Human (FIH) projections and narrowing the “translational gap.”
- Translational Confidence: Hard-coding predictive power into candidate selection to streamline regulatory transitions.
May 21
Comparing Mouse Models for Metabolic Disease: Diabetes, Obesity, and MASH
- How different mouse models capture different facets of human metabolic disease
- Why the same mutation on different genetic backgrounds can elicit different phenotypes
- Sex differences and sex similarities in various metabolic models
- How different models can be useful for GLP-1 therapeutic studies
May 27
Functional Ultrasound Demonstration and Live Q&A: Iconeus One, a Pioneer in Real-Time Whole-Brain Imaging
- Demonstration of functional ultrasound (fUS) with the Iconeus One system
- Showcase of different possible neuroscience applications
- Introduction to ultrasound localization microscopy (ULM)
May 27&28
Advancing the drug discovery and development pipeline
Increasing biological complexity, data integration challenges, and evolving regulatory expectations are influencing how researchers identify targets, optimize candidates, and design clinical studies. This two-day symposium will bring together leading experts discussing emerging strategies, technologies, and collaborations that are transforming drug discovery and development across the pharmaceutical industry.
June 3
Endpoints at #ASCO26
We're assembling a panel of oncology insiders to break down the readouts to watch and where the field is actually headed over the next year.
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Novel Approach Methodologies / Microphysiological Systems
May 13
Developing Solutions for Organoid Challenges
- How to overcome tissue structure heterogeneity in organoid generation
- How the unique mechanisms used by mammals, birds, and reptiles to build lung epithelium inspire strategies for building organoids
- How micropatterned human pluripotent stem cell-derived gastruloids enable in vitro modeling of early-stage cardiac and hepatic vascularization
May19
Ask the Experts: An Independent View on MPS Trends, Challenges, and Opportunities Ahead
This panel webinar brings together consultants from the 3RsC‑MPS Initiative to discuss the current state of the MPS field, where it is gaining traction as a possible replacement for traditional animal models, and what is needed to advance broader and more effective use.
May26
Building regulatory confidence with immune‑competent microphysiological systems
Topics to be covered:
- Shifting regulatory frameworks and the accelerated acceptance of MPS for decision-making
- Benchmarking liver MPS performance using data from an FDA Innovative Science and Technology Approaches for New Drugs (ISTAND)–accepted cross-platform evaluation project
- Achieving long-term in vitro safety insights with continuously perfused human liver microtissue systems
- Utilizing immune-competent liver and lung platforms to capture human-specific toxicities that are poorly predicted by animal models
June 2
Detecting Early Synaptic Failure in Prion Disease Using Organoid Models
- Early synaptic dysfunction is a shared hallmark of prion disease across mouse and human models.
- Disease-associated prion protein mutations drive early synaptic abnormalities in inherited prion disorders.
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Advanced electrophysiology technology, like Mesh MEA, helps track synaptic damage and understand prion neurodegeneration mechanisms.
June 10
Light Sheet Imaging in Cardiac Disease Models
- Light sheet microscopy for intact cardiac tissue imaging
- Visualization of contractility and calcium dynamics
- Application of cardiac organoids in research
- Integration of imaging with functional assays
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Business Development
Stay Tuned
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