The Community News Page: Provides current updated information on upcoming webinars and news in the areas of comparative and translational medicine, novel alternative methods, laboratory animal sciences, theronostics, and nonclinical sciences.
Please feel free to offer suggestions on upcoming events and current news items that you find interesting to: biovetality@gmail.com
EVENTS
Dec12
Gut Microbial Metabolites and Their Impact on Host Systems
https://isbscience.org/events/2025-isb-virtual-microbiome-symposium/
In this symposium, we will hear from leading experts who will present their groundbreaking work on how specific microbial metabolites influence neural, immune, and endocrine systems.
Dec 5: Public Workshop: Pediatric Developmental Safety Assessment and New Approach Methodologies (8:00-4:00 ET) UNC Eshelman School of Pharmacy
"... the reliance on juvenile animal testing for all pediatric preclinical assessments has run into both the realization of the limitations to this assessment plus the need to develop new approach methodologies (NAMs) to animal testing expressed by the US FDA and multiple federal agencies."
Dec 4 Leadership Under Pressure: How Biotech Executives Are Turning Complexity into Momentum
Dec 3: MPS in Drug Development sponsored by the 3RsC and IQ-MPS Affiliate
- Hear real-world case studies from leading companies whose MPS platforms supported regulatory submissions.
- Gain insights into how MPS can advance drug development and improve safety predictions.
- Connect with experts shaping the future of NAMs in science.
- https://email.3rc.org/tf/cl/eyJ2Ijoie1wiYVwiOjczNzU3MSxcImxcIjoxNzAyNDUzODAyNjk2NzIzOTYsXCJyXCI6MTcwMjQ1Mzk2ODk3OTkwNTIyfSIsInMiOiIyNzBmNzJlMzkwZWM1M2U1In0
Dec 4: Preclinical Operational Advantages of Digital Home Cage Monitoring: Smarter Insights, Streamlined Science
1:00 PM ET (New York) Chief Veterinary Officer of The Jackson Laboratory, will explore how Envision’s computer vision–based digital caging platform enables continuous, non-invasive monitoring of individual mice directly from the home cage—capturing detailed behavioral and activity patterns without disrupting normal routines. https://jackson.jax.org/jax-event-12042025.html?utm_source=marketo&utm_medium=email&utm_campaign=2025_12_04_webinar&utm_content=invite_1
Self Paced Course (Free): This intensive course, developed by the International Society for Stem Cell Research (ISSCR), offers a comprehensive exploration of key topics in stem cell medicine. Designed for clinicians, medical students, and health care professionals, the curriculum is structured into seven modules providing an overview of the field, from basic stem cell biology and clinical trials to ethical considerations surrounding unproven stem cell interventions and patient communication. https://www.isscr.org/isscr-news/the-isscr-launches-first-online-global-continuing-education-course
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Moved to On Demand
Nov 19: Targeted Expression Profiling Reveals Biomarkers Associated with Poor Prognosis and Therapy Resistance of Glioblastoma
Demonstrating the use of large biomarker profiling and tumor organoids Link Pending
What you will learn
- How targeted gene expression profiling using the Standard BioTools Biomark System uncovered novel biomarkers linked to patient prognosis
- Insights into distinct molecular signatures across tumor regions highlighting the complexity of GBM and its invasive behavior
- How patient-derived organoids replicate treatment-induced DNA-damage responses for translational model development
Nov 11: Gain Efficiencies in Your DART Programs with Newly Developed NAMs Assays (Charles River Sponsor)
Very interesting webinar: On-Demand Link: https://www.criver.com/webinar-series-sa-advance-your-dart-programs-new-approach-methodologies-nams?utm_source=samktg&utm_medium=email&utm_campaign=sa-wbr-dart-series-wbr2-replay-nov2025
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Vitalizing News, Publications & Commentary
11/25/2025
A remarkable story on the success of gene therapy in in juvenile https://www.bbc.com/news/articles/c5y0y56x6veo This is so needed after decades of struggling to perfect this treatment modality.
11/23/2025
Scientist engineer a fungus to produce meatlike proteint: https://scitechdaily.com/crispr-supercharges-a-meatlike-fungus-into-a-sustainable-protein-powerhouse/
As several policies are being developed to reduce animal use in biomedical technology other groups are developing alternatives to meat derived from agriculture. If successful at developing a pallatable meatlike product and NAMs advance, how do you picture the effects on human culture and perspectives on animal use in the future?
11/20/2025
Penn veterinarian discovered a simple way to prevent heat stroke in dogs
https://www.phillyvoice.com/preventing-heat-stroke-dogs-head-dunk-cynthia-otto-penn-vet/
Dogs can be trained to dunk their head in water, and there's a video to show how the training is done. Dogs have limited ways of cooling off through panting and their footpads. This innovation is great for working or athletic dogs that may be at risk for overheating.
11/20/2025
Pfizer's mRNA flu vaccine shows 34.5% greater efficacy than standard shot in phase 3 https://www.fiercebiotech.com/biotech/pfizer-details-phase-3-data-mrna-flu-vaccine?utm_medium=email&utm_source=nl&utm_campaign=LS-NL-FierceBiotech&oly_enc_id=2170I9070434G3S
The study revealed slightly more side effects with mRNA. Seems that there is a correlation between side-effects and efficacy. Is a slight increased risk of getting flu-like symptoms the day after worth the a potential 34% gain in efficacy?
11/11/2025
MIT researchers are developing a mulit-drug staggered delivery chip that has shown efficacy in repairing damaged heart tissue in a rat model. The chip is being developed to restore tissue in patients that have experienced a heart attach MIT engineers develop drug delivery patch for heart attack healing
A great example of how the in vivo (surgical model) applications have combined with microphysiological systems (proof-of-concept) to advance a potential treatment for cardiac patients.
11/07/25 Heart on a chip: A great example of a microphysiological system application in testing a new nanoparticle delivery system. The group show that the nanoparticles penetrate into the in cardiac muscle and deliver mRNA.
With data from MPS systems, investigators can build confidence in their systems and possibly reduce animal numbers when it comes to in vivo testing.
11/02/25
Radiopharmaceutical clinical trials increase ten fold over the last seven years
Pluvicto, a radiopharmaceutical targeting PMSA has been getting great success in treating metastatic prostate cancer. Other targeted radiotherapeutics are sure to follow. Novartis’ Pluvicto Heavywork Proves Radiopharma Can Succeed - BioSpace
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Did you know that the American Association for Veterinary Medicine keeps a registry of veterinary clinical trials?
Moved to our Links page as a permanent reference.
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