Coke Cola Enema

https://www.auntminnie.com/clinical-news/ct/article/15822953/ct-reveals-new-use-for-coke-dissolving-massive-fecalomas?utm_campaign=2026-04-23&utm_source=AuntMinnie-Letter+From+The+Editor&since=1777006800000&braze_int_id=689e14ab43f4c80058f49d1e&braze_ext_id=6998ec09a3325c250774f996&utm_medium=email

A case study where  Coca-Cola was shown to be effective as an enama to resolve fecaloma in a patient

Classic Coca-Cola acts as a mucolytic agent, a source of carbonic acid, and an effervescent solvent. It has traditionally been used to dissolve solid, indigestible masses of plant fiber that accumulate in the stomach, and some research has suggested that it could also dissolve fecalomas.


FDA approves Regeneron’s hearing loss gene therapy

https://www.npr.org/2026/04/22/nx-s1-5791478/gene-therapy-deafness-hearing   

https://www.biopharmadive.com/news/regeneron-fda-otarmeni-hearing-loss-gene-therapy-voucher/818345/?utm_source=Sailthru&utm_medium=email&utm_campaign=Newsletter%20Weekly%20Roundup:%20BioPharma%20Dive:%20Daily%20Dive%2004-25-2026&utm_term=BioPharma%20Dive%20Weekender   

Otarmeni is the first FDA-approved gene therapy for patients with sensorineural hearing loss caused by OTOF (otoferlin) genetic mutations. OTOF is necessary for hair cells in the inner ear to transmit sound signals to the brain.   As a one-time, surgically delivered intracochlear injection, it works by introducing a functional OTOF gene to enable sound signaling, often restoring significant hearing.



Advances in pancreatic and potentially other cancers by targeting Ras

https://www.fiercebiotech.com/biotech/revolutions-much-hyped-ras-inhibitor-hits-key-survival-goals-phase-3-pancreatic-cancer

and 

https://www.fiercebiotech.com/biotech/aacr-revolution-rolls-pancreatic-cancer-ras-wave-rises?utm_medium=email&utm_source=nl&utm_campaign=LS-NL-FierceBiotechResearch&oly_enc_id=2170I9070434G3S

Revolution Medicine’s Daraxonrasib was reported to have a mean increased overall survival of 6 months in a phase 3 pancreatic cancer study.   Daraxonrasib acts as a glue that sticks Ras to another protein, cyclophilin A, which shuts off Ras’ ability to drive cell growth and division.


Metastases travel in cell clusters!


https://www.science.org/content/article/roaming-gangs-tumor-cells-help-spread-cancer-can-drugs-break-them  


Better opportunity to lodge in tissues and autocrine factors remain localized.


Chinese scientists unveil glowing Avatar-like plants that could light cities without electricity    

https://www.euronews.com/next/2026/04/02/chinese-scientists-unveil-glowing-avatar-like-plants-that-could-light-cities-without-elect


 Catmint oil  in the fight against avian influenza?

USDA is betting $2M on it

https://www.michiganfarmnews.com/can-catmint-oil-help-in-fight-against-avian-influenza-usda-is-betting-2m-on-it

The oil contains nepetalactone, which exhibits antimicrobial, antioxidant, and antiviral properties. Application is by fogging chicken houses.

 


Tick saliva protein vaccine


https://www.drugdiscoverynews.com/tick-saliva-fuels-new-vaccine-development-16330?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz--Aag_KUw-nGln8V_q2D3C7LfPgjn-wB-OvVBITEykQVxNXIMptsA_kVxVVdWZJtnqQMM05AjNVdf5qk07qsbpipkDbtA&_hsmi=413261662&utm_content=413261662&utm_source=hs_email 


When a blacklegged tick (Ixodes scapularis) sinks its mouthparts into a person’s skin, it releases a variety of salivary proteins. Some of these proteins suppress the innate immune response that would otherwise try to get rid of the tick and any invading microorganisms it might be carrying” By developing a vaccine to these proteins, the inflammatory response may alert the host to the ticks presence and cause it to detach before transmission of infectious disease, such as lyme disease.


Migraine Treatment

https://www.healthday.com/health-news/neurology/newer-migraine-drugs-reduce-headache-days-with-fewer-side-effects

New research shows CGRP-targeted therapies can help migraine sufferers

These medications block a protein that spikes during migraines, triggering pain


Hantavirus in Argentina

https://apnews.com/article/argentina-hantavirus-cruise-ship-5841c25be9aa6dd3cd6edc81c74609de

The Argentine Health Ministry has reported 101 hantavirus infections  in the last year, roughly double that of the previous year.  Climate change has been implacated as a posible contributing factor to rodent populations spreading to human inhabited áreas.

Vaccine development

has be slow due to relatively low incidence of the disease to conduct clinical trials.

https://www.nature.com/articles/d41586-026-01494-9


PDX Cancer Models and Radiopharmaceutical Collaboration

https://bioemtech.com/bioemtech-and-certis-oncology-announce-partnership-to-provide-pdx-models-for-radiopharmaceutical-preclinical-studies/

Radiopharmaceutical development continues on its rapid path.  This is an interesting collaboration to provide translational cancer models for testing and development of therapeutics.

Create Your Own Website With Webador